Description:
Dark blue crystalline powder in solution with water or alcohol. Used in in the treatment of methemoglobin toxicity. Acts as reducing agent to convert iron in methemoglobin from Fe +++ to Fe++, regenerating normal hemoglobin.
Indications:
Treatment of severe symptomatic methemoglobinemia.
Contraindications:
Cyanide poisoning is a contraindication to use.
Adverse Effects:
Nausea, vomiting, abdominal and chest pain, headache, dizziness, confusion, dyspnea, hypertension.
Dosage:
7ml ( 0.1ml/kg of 1% soln ) IV over 2-3 minutes with NaCl running at 200-300ml/hr. May repeat in 10 minutes if not improved.
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